ABSTRACT
The aim of this study was to evaluate the residual activity of treated dog's hair coat with dinotefuran on larvae and adults of Ctenocephalides felis felis. Three female Beagle dogs were used. One female dog was treated with 0.834 percent dinotefuran spray, the second was treated with 30 percent dinotefuran strip-on and the third was not treated. Some areas of dog's hair were clipped on days 2, 9, 16, 23, 30, 37 and 44 after treatment. For the evaluation of adulticidal and larvicidal activities, flea adults and larvae from the laboratory colony were used. Six repetitions were used with 10 samples of each flea stage per day, placed in assay tubes. In each repetition we added 0.02 g of treated or untreated dog's hair and larval diet for the immature stage. Flea adult assay was evaluated with 24 hours and the flea larvae 20 days after treatment. The residue on hair coat of both treated dogs showed efficacy on the flea larvae control for 44 days. Regarding the flea adults control the spray and strip-on formulations showed efficacy until days 16 and 23, respectively.
O objetivo deste trabalho foi avaliar a atividade in vitro do resíduo em pelo de cobertura de cães tratados com dinotefuran sobre larvas e adultos de Ctenocephalides felis felis. Foram utilizadas três cadelas da Raça Beagle: a nº 1 foi tratada com uma formulação spray de dinotefuran a 0,834 por cento, a nº 2 com uma formulação "strip-on" de dinotefuran a 30 por cento e a nº 3 foi mantida sem tratamento. Pequenas áreas foram tricotomizadas nos dias 2, 9, 16, 23, 30, 37 e 44 após o tratamento. Para avaliação adulticida e larvicida, foram utilizados pulgas de uma colônia mantida em laboratório. Seis repetições com cada uma contendo 10 exemplares de C. f. felis, acondicionados em tubos de ensaio, da etapa correspondente foram utilizados por dia de desafio. Em cada repetição foi adicionado 0,02 gramas de pelo de cada área tricotomizada e dieta na etapa de larvas. O material da etapa adulto foi avaliado num período de 24 horas, o da etapa larvas foi avaliado após 20 dias de cada desafio. O resíduo no pêlo de cães tratados com ambas as formulações de dinotefuran foi eficaz no controle de larvas por um período de 44 dias, e no controle de adultos as formulações spray e a "strip-on" foram eficazes por um período de 16 e 23 dias, respectivamente.
Subject(s)
Animals , Dogs , Guanidines/pharmacology , Hair/parasitology , In Vitro Techniques , Nitro Compounds/pharmacology , Siphonaptera/drug effects , Larva/drug effectsABSTRACT
Se presenta un paciente con tungiasis múltiple que fue tratado con ivermectina por vía oral y se obtuvo una excelente respuesta terapéutica, sin efectos colaterales indeseables, Este fármaco hasta el momento no fue utilizado en el tratamiento de esta enfermedad. Se efetúa una revisión de la tungiasis, así como de las indicaciones y mecanismo de acción de la ivermectina
Subject(s)
Humans , Male , Adult , Foot Dermatoses/parasitology , Ivermectin/therapeutic use , Siphonaptera/pathogenicity , Toes/pathology , Foot Dermatoses/drug therapy , Foot Dermatoses/etiology , Ivermectin/administration & dosage , Siphonaptera/drug effects , Thiabendazole/therapeutic useABSTRACT
The insecticidal activity, expressed by LD50 values, of acetone, ethanol, petroleum ether and water extracts of Calotropis procera leaves against the flesh fly, Sarcophaga hemorrhoidalis Fallen was evaluated in the laboratory. Based on LD50 values, ethanol extract was nearly 1.7, 1.3 and 1.3 times more toxic to larvae than water, petroleum ether and acetone extracts, respectively. It was 1.9, 1.4 and 1.2 times more toxic to pupae than water, acetone and petroleum ether extracts, respectively. It was 2, 1.5 and 1.4 times more toxic to male flies and 2.2, 1.6 and 1.4 times more toxic to female flies than water, petroleum ether and acetone extracts, respectively. Thus, ethanol extract of C. Procera was the most toxic, of all solvents used, to different stages of S. hemorrhoidalis. The findings suggested also that C. procera extracts may produce larvicidal, pupicidal and adulticidal effects [as general toxicants] against the flesh fly, S. hemorrhoidalis